We develop statistical and machine-learning methods for understanding complex data, making reliable decisions, and supporting scientific discovery.
Our lab led by Jin-Hong Du works at the intersection of statistics, machine learning, and data-driven science. Our research combines rigorous statistical theory with modern computational methods to address problems involving causality, interpretability, distribution shifts, and complex structured data.
Our current research includes:
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Causal inference Identification, semiparametric inference, treatment-effect estimation, transportability, and causal learning under weak assumptions.
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Reliable and interpretable machine learning Feature importance, uncertainty quantification, distribution-shift robustness, and principled evaluation of machine-learning systems.
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High-dimensional and structured data Statistical methods for networks, time series, latent-factor models, functional data, and other complex dependent data.
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AI for scientific discovery Machine learning for single-cell genomics, perturbation modeling, biomedical research, and other scientific applications.
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Foundation models and intelligent systems Statistical foundations for reasoning, causal representation, out-of-distribution generalization, and verifiable evaluation of foundation models and agents.
This organization hosts:
- Research software and reproducible implementations
- Code accompanying our papers and preprints
- Simulation and benchmarking frameworks
- Tutorials, examples, and research resources
- Collaborative projects developed by lab members
Repositories will include documentation, reproducibility instructions, and licensing information whenever possible.
We aim to build methods that are:
- Statistically principled
- Computationally practical
- Transparent and reproducible
- Robust to real-world complexity
- Relevant to substantive scientific questions
We welcome collaborations across statistics, machine learning, artificial intelligence, genomics, and data-intensive scientific disciplines.
For research information, publications, and updates, visit Jin-Hong Du’s website.
Theory with purpose. Methods that survive contact with data.